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Intramuscular piperacillin sodium in uncomplicated lower urinary tract infections: Evaluation of safety, clinical and bacteriological responses and blood levels

par Schoutens, ELISABETH;Potvliege, Catherine ;Yourassowsky, Eugène
Référence Current therapeutic research, 26, 6, page (848-855)
Publication Publié, 1979

Article révisé par les pairs

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Résumé :

Twenty hospitalized adults with lower urinary tract infections received piperacillin sodium intramuscularly 2 grams every 12 hours for 6 to 8 days. Eradication of the causative pathogen was achieved in all patients and was maintained in 14 of them for at least 6 weeks. The mean peak serum level, determined one hour after the 2-gram intramuscular dose, was 40 ug/ml (11-94). Minor side effects were observed including a slight and reversible elevation of blood urea in 3 subjects who had received - concurrently or recently - moderate doses of furosemide.