par Meilhac, Sigolène S.M.;Buckingham, Margaret;Lescroart, Fabienne 
;Blanpain, Cédric
Référence Cold Spring Harbor Perspectives in Medicine, 4, 9, a013888
Publication Publié, 2014
;Blanpain, Cédric Référence Cold Spring Harbor Perspectives in Medicine, 4, 9, a013888
Publication Publié, 2014
Article révisé par les pairs
| Résumé : | Myocardial cells ensure the contractility of the heart, which also depends on other mesodermal cell types for its function. Embryological experiments had identified the sources of cardiac precursor cells.With the advent of genetic engineering, novel tools have been used to reconstruct the lineage tree of cardiac cells that contribute to different parts of the heart, map the development of cardiac regions, and characterize their genetic signature. Such knowledge is of fundamental importance for our understanding of cardiogenesis and also for the diagnosis and treatment of heart malformations. |
