Résumé : Background and Objectives: The aim of this study was to observe the morphological characteristics of dentin-resin interfaces when a composite resin was bonded to Er:YAG laser irradiated dentin. Study Design/Materials and Methods: Human dentin surfaces were divided into three equal areas. One third was prepared using a carbide bur and etched with phosphoric acid, the second third was conditioned using an Er:YAG laser, the third one was irradiated and etched. A hybrid composite resin was bonded on dentin surfaces using a single-component adhesive system. Longitudinal sections were exposed to 5 N HCl then to 1% NaOCl. The thickness of the hybrid layer and the dimensions of the resin tags were measured using scanning electron microscopy (SEM) pictures and an image analysis software. Results: When acid etching was performed, a hybrid layer as well as the characteristic funnel-shaped resin tags were observed. When Er:YAG laser was used alone, no hybrid layer could be detected. The resin tags appeared thinner and exhibited a cylindrical shape. Conclusions: The acid pre-treatment of the irradiated surface allowed both the seal of the dentinal surface and the increase of the diameter of the resin tags. © 2004 Wiley-Liss,Inc.