par Paiva, Manuel
Référence Clinical Respiratory Physiology, 18, 2, page (189-201)
Publication Publié, 1982
Article révisé par les pairs
Résumé : The one-trumpet model and the assumptions underlying it are described. One of its most interesting predictions - the stationary front - is analysed in more detail, particularly with respect to the expansibility of the geometrical boundaries. The improvements due to the two-trumpet model and the concept of interdependence of pulmonary gas transport are discussed. Recent findings when using asymmetrical units are presented: the intra-acinar asymmetry can produce a sloping alveolar plateau, a 'diffusive Pendelluft' effect, a 'first in-last out' pattern of breathing. Furthermore, the slope of the alveolar plateau is very sensitive to the cross-section narrowing inside the acinus. Finally, a multi-branch point model representing the acinus according to Hanse and Ampaya anatomical data is described and used to study the time of gas mixing equilibration during breath-holding. It appears to be higher than predicted from the one-branch point model.