par Yernault, Jean Claude 
;Vandevivere, Johan
Référence Clinical Respiratory Physiology, 16, 3, page (411-420)
Publication Publié, 1980
;Vandevivere, JohanRéférence Clinical Respiratory Physiology, 16, 3, page (411-420)
Publication Publié, 1980
Article révisé par les pairs
| Résumé : | Regional lung function has been studied with xenon-133 in 25 adult patients with different types of heart disease. In cases of mitral and aortic valve disease, perfusion and ventilation tend to be shifted from the lung bases towards the apices, more markedly so when the pulmonary wedge pressure is elevated. The primum movens of these changes seem to be accumulation of extravascular lung water in the bases, the anatomical lesions of the vessels playing a complementary role. In cases of congenital heart disease the pulmonary artery pressure level also influences regional perfusion, whereas ventilation seems little affected. Nine children with complex congenital heart malformations were also studied with a krypton-81m ventilation lung scan as well as classical perfusion scintigraphy. When the former is usually normal, localized perfusion defects were found in each case, some of them probably being secondary to palliative surgical procedures. |
