par Danis, André
Référence Bulletin et mémoires de l'Académie royale de médecine de Belgique, 156, 1-2, page (107-112)
Publication Publié, 2001
Article révisé par les pairs
Résumé : Distraction osteogenesis relies on two local factors: 1 degree mechanical stretching multiplicates the fibroblastic population; 2 degrees hypoxia, by vessel elongation and cellular compaction, induces osteogenic stress protein metabolism. Progressive return to aerobic conditions assumes permanency of the new osseous structures. The precise technical procedure of Ilizarov brings under control the osteogenic process with unprecedented human clinical results.