Influence of the sialic acid content of membranes on their sensitivity to silica and aluminate-modified silica

Depasse, Jacques

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Influence of the sialic acid content of membranes on their sensitivity to silica and aluminate-modified silica

par Depasse, Jacques

Référence Environmental research, 16, 1-3, page (88-91)
Publication Publié, 1978

Article révisé par les pairs

Résumé :

The hemolytic activities of silica and aluminate-modified silica (AM silica) have been tested. Sheep erythrocytes are equally sensitive to silica and AM silica. Horse erythrocytes are more resistant than sheep erythrocytes, and more sensitive to silica than to AM silica. After neuraminidase treatment, the behavior of horse erythrocytes becomes nearly the same as that of sheep erythrocytes. It appears that the sensitivity of the cell to silica or aluminated silica is strongly dependent on the sialic acid content of the membrane. This observation may be related to the strong influence of the aluminum content of silica on its in vivo toxicity.

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