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Microbial contamination and sick building syndrome

par Michel, Olivier ;Ginanni, Roberta
Référence Aerobiologia, 6, 1, page (51-53)
Publication Publié, 1990-06

Article révisé par les pairs

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Résumé :

Permanence within a building is frequently associated with health complaints identified as several clinical syndromes. Contamination by bacterial products may play a predominant role in some of these clinical syndromes, like building-related asthma, humidifier fever or the sick building syndrome (SBS). Indeed, on one side, in air-conditioned systems, the physical conditions are optimal for microbial development and for endotoxin production (from the membrane of gram negative bacteria) and on the other side, inhalation of endotoxin has demonstrated the onset of a bronchial obstruction and an increase in airway reactivity leading to non specific chest complaints. Nevertheless, this hypothesis on aetiopathogenesis of SBS remains to be demonstrated by environmental and lung functional studies on the building site. © 1990 Kluwer Academic Publishers.