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Pulse steroid therapy for children's severe Alopecia areata?

par Kiesch, Nelly ;Stene, Jean Jacques ;Goens, Jean ;Vanhooteghem, Olivier;Song, Micheline
Référence Dermatology, 194, 4, page (395-397)
Publication Publié, 1997

Article révisé par les pairs

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Résumé :

Seven children with severe, rapidly evolving alopecia areata (AA) were treated with pulse Steroid therapy (PST). AA had been present for 3-44 weeks and involved more than 30% of the scalp. One patient had alopecia totalis. Intravenous methylprednisolone (5 mg/kg twice a day) administered for 3 days. No serious side effects were noted. At the 12-month follow-up, complete regrowth had occurred in 5 patients (71%). The patient with alopecia totalis had no regrowth. PST appears to be a promising and safe treatment for extensive, recent-onset AA in children. No response is to be expected in alopecia totalis or long-standing AA.