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Évaluation analytique du dosage sérique de la phosphatase alcaline osseuse par le test Access Ostase™-Beckman/Coulter et comparaison au test Tandem®-Ostase Beckman/Coulter

par Cheblal, Habiba ;Barle, Josette
Référence Immuno analyse & biologie spécialisée, 17, 3, page (181-184)
Publication Publié, 2002-06

Article révisé par les pairs

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Résumé :

The markers of bone remodeling are useful in the control of the diseases of the bone tissue metabolism. Bone-specific alkaline phosphatase (bone ALP) is a constituent of the osteoblast, marker of the bone formation. We compared the serum bone ALP measurements with two immunoassay-methods: Access Ostase™-Beckman/Coulter and the immunoradiometric Tandem®-Ostase Beckman/Coulter method (IRMA). We observed a good correlation between the two methods. The test Access Ostase™-Beckman/Coulter, method sandwich immunoenzymatic is simple, rapid, providing an exploration of the bone turn-over, complementary to the densitometric techniques which measure the bone mass. It also supports a saving of time in the follow-up of the patients. © 2002 Éditions scientifiques et médicales Elsevier SAS. All rights reserved.