par Demaubeuge, Josiane ;Tennstedt, Dominique;Broux, R.
Référence Dermatologica, 164, 6, page (386-394)
Publication Publié, 1982
Référence Dermatologica, 164, 6, page (386-394)
Publication Publié, 1982
Article révisé par les pairs
Résumé : | A new type of antiallergic drug, oxatomide (60 mg daily), was compared with the antihistaminic, mequitazine (10 mg daily), in a 5-week double-blind randomized study involving 26 patients with chronic urticaria. In the 13 oxatomide-treated patients, papules, erythema and pruritus were significantly suppressed after 2 weeks, which was markedly more rapid than with mequitazine. Slight somnolence was reported by 3 patients on oxatomide and 1 on mequitazine; in the latter case, severe urine retention was also reported. Another patient on mequitazine had to discontinue treatment because of severe drowsiness. |