Résumé : SELENE (SELf-rewetting fluids for thermal ENErgy management) is a microgravity experiment proposed to the European Space Agency (ESA) in response to the Announcement of Opportunities for Physical Sciences. Main objectives of the microgravity research onboard the International Space Station (ISS) include the quantitative investigation of heat transfer performances in model heat pipes and validation of adequate theoretical and numerical models. In particular the research is focused on "self-rewetting fluids", i.e. fluid mixtures with unusual surface tension properties. This article summarizes preliminary ground-based research activities in preparation of the microgravity experiments. They include: (1) thermophysical properties measurements; (2) study of thermo-soluto-capillary effects in micro-channels; (3) numerical modeling; (4) measurements with optical (e.g. interferometric) and intrusive techniques; (5) surface tension-driven effects and thermal performances test on different capillary structures and heat pipes; and (6) breadboards development and support to definition of scientific requirements. © 2013 IAA.