par Bourgeois, Pierre ;Khodadadi, E.;Malarme, Marianne ;Feremans, Walter
Référence Nuc compact, compact news in nuclear medicine, 21, 4, page (159-162)
Publication Publié, 1990
Article révisé par les pairs
Résumé : Four patients with histologically proven hepatocellular carcinomas (HCC) have been scintigraphically investigated using Iodine-123-labeled insulin. All had increased serum alpha-foetoprotein values. In three patients, hepatic space occupying lesions were demostrated by X-ray computed tomography (CT). The lesions were detected by ultrasonography in 2 cases and by Tc-99m colloid Single Photon Emission Computed Tomography (SPECT) in all cases, carcinomatous lesions exhibited increased and prolonged insulin uptake with reference to normal liver tissue. These studies have shown that I-123-labeled insulin has potential value as imaging agent for the in vivo diagnosis of HCC.