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X-ray structure of the dimeric bis[(1,7-dicarba-closo-dodecaborane-l-carboxylato)-di-n-butyltin] oxide

par Gielen, Marcel ;Bouhdid, Abdeslam;Willem, Rudolph ;Bregadze, Vladimir V.I.;Ermanson, Lidia;Tiekink, Edward E.R.T.
Référence Journal of organometallic chemistry, 501, 1-2, page (277-281)
Publication Publié, 1995-10

Article révisé par les pairs

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Résumé :

X-ray diffraction studies reveal the structure of {[(1,7-C2B10H11-1-COO)Bu2Sn]2O}12 to be analogous to most other {[RCOO)Bu2Sn]2)O}2 compounds. The dimer features a central Bu4Sn2O2 unit with the two Bu2Sn groups being linked via bridging oxygen atoms, each of which also carries an exocyclic Bu2Sn moiety. The two pairs of exo- and endo-cyclic tin atoms are each linked via a symmetrically bridging carboxylate ligand and the two remaining ligands coordinate the exocyclic tin atom only, in the monodentate mode. The in vitro anti-tumour activity of this compound, against a variety of cell lines, is compared with those of clinically used compounds. ? 1995.