Résumé : To investigate cardiovascular adaptation to transient microgravity (μG), we measured RR intervals (RRI), arterial blood pressure (BP), pulse wave transit time (PTT) and systolic time intervals (STI) during parabolic flight. Our results demonstrate that during μG RRI, BP and PTT are subject to a rapid adaptation likely mediated by the baroreflex whereas STI changes with μG but does not present further adaptation.