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Action of trypsin on Rh-positive human red cells [7]

par Hubinont, Pierre-Olivier
Référence Nature (London), 167, 4242, page (278)
Publication Publié, 1951

Lettre à l'éditeur

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Résumé :

IT is well known since the work by Pickles1, and Morton and Pickles2, that cholera filtrates and trypsin alter the Rh-positive cells with the result that they become agglutinable in saline by anti-Rh pure blocking antibodies. On the other hand, Race and Sanger3 have recently described a chromosome alteration in an individual lacking all antigens at the Cc and Ee loci, with an extraordinarily strong D antigen, as judged by its avidity for anti-D. This particular blood was found to be agglutinated by pure blocking anti-D diluted in saline. © 1951 Nature Publishing Group.