par Platteborse, René ;Hermans, Cédric;van Loon, Jef
Référence Postgraduate medical journal, 55, Suppl. 1, page (15-18)
Publication Publié, 1979
Article révisé par les pairs
Résumé : In a study in dogs using ultrasonic transducers to measure degree of pyloric dilatation, it was found that i.v. domperidone (0.35 and 0.7 mg/kg) significantly increased the diameter of the pyloric lumen without affecting the frequency of pyloric relaxations. A subsequent study involving 59 patients referred for upper digestive tract endoscopy, confirmed this increase in diameter of the pylorus which indicates a potential use of domperidone (either i.v. or oral) in the treatment of some forms of dyspepsia characterized by delayed gastric emptying.