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Sleep anomalies in the chronic fatigue syndrome. A comorbidity study

par Fischler, Benjamin;Le Bon, Olivier ;Hoffmann, Guy;Cluydts, Raymond;Kaufman, Leonard;De Meirleir, Kenny
Référence Neuropsychobiology, 35, 3, page (115-122)
Publication Publié, 1997-04

Article révisé par les pairs

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Résumé :

Polysomnographic findings were compared between a group of patients with the chronic fatigue syndrome (CFS; n = 49) and a matched healthy control (HC) group (n = 20). Sleep initiation and sleep maintenance disturbances were observed in the CFS group. The percentage of stage 4 was significantly lower in the CFS group. A discriminant analysis allowed a high level of correct classification of CFS subjects and HC. Sleep-onset latency and the number of stage shifts/hour contributed significantly to the discriminant function. The presence of these anomalies as well as the decrease in stage 4 sleep were not limited to the patients also diagnosed with fibromyalgia or with a psychiatric disorder. No association was found between sleep disorders and the degree of functional status impairment. The mean REM latency and the percentage of subjects with a shortened REM latency were similar in CFS and HC.