Titre :
  • PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic bata-cell apoptosis via regulation of the BH3-only protein Bim.
Auteur : Santin, Izortze ; Moore, Fabrice ; Colli, Maikel L ; Gurzov, Esteban Nicolas ; Marselli, Lorella ; Marchetti, Piero ; Eizirik, Decio L.
Informations sur la publication : Diabetes, 60, 12, (page 3279-3288)
Statut de publication : Publié, 2011
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Aged
Animals
Apoptosis -- drug effects -- genetics
Apoptosis Regulatory Proteins -- genetics -- metabolism
Blotting, Western
Cell Survival -- drug effects -- genetics
Cells, Cultured
Diabetes Mellitus, Type 1 -- genetics -- metabolism
Fluorescent Antibody Technique
Humans
Insulin-Secreting Cells -- cytology -- metabolism
Interferon-alpha -- pharmacology
Interferon-beta -- pharmacology
Membrane Proteins -- genetics -- metabolism
Protein Tyrosine Phosphatase, Non-Receptor Type 2 -- genetics -- metabolism
Proto-Oncogene Proteins -- genetics -- metabolism
RNA Interference
Rats
STAT1 Transcription Factor -- genetics -- metabolism
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0012-1797 
info:doi/10.2337/db11-0758
info:pii/db11-0758
info:pmid/21984578
info:pmcid/PMC3219938