Titre :
  • Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes.
Auteur : Igoillo Esteve, Mariana ; Marselli, L ; Andrade Da Cunha, Daniel ; Ladrière, Laurence ; Ortis, Fernanda ; Grieco, Fabio Arturo ; Dotta, F ; Weir, G. ; Marchetti, Piero ; Eizirik, Decio L. ; Cnop, Miriam
Informations sur la publication : Diabetologia, 53, 7, (page 1395-1405)
Statut de publication : Publié, 2010
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Chemokine
Cytokine
Endoplasmic reticulum
Fatty acid
Inflammation
Interleukin-1β
Islet
Palmitate
Pancreatic beta cell
Type 2 diabetes
Mots-clés MeSH : Aged
Cell Line
Chemokine CCL2 -- metabolism
Chemokine CXCL1
Diabetes Mellitus, Type 2 -- metabolism
Enzyme-Linked Immunosorbent Assay
Female
Fluorescent Antibody Technique
Humans
Insulin-Secreting Cells -- metabolism
Interleukin-6 -- metabolism
Interleukin-8 -- metabolism
Islets of Langerhans -- drug effects -- metabolism
Male
Middle Aged
NF-kappa B -- metabolism
Oligonucleotide Array Sequence Analysis
Palmitates -- pharmacology
Polymerase Chain Reaction
Radioimmunoassay
Tumor Necrosis Factor-alpha -- metabolism
Note : In Vitro
Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0012-186X 
info:doi/10.1007/s00125-010-1707-y
info:pmid/20369226