Titre :
  • Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers?
Auteur : Florence, Xavier ; Desvaux, Vincent ; Goffin, Eric ; de Tullio, Pascal ; Pirotte, Bernard ; Lebrun, Philippe
Informations sur la publication : European journal of medicinal chemistry, 80C, (page 36-46)
Statut de publication : Publié, 2014-04
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Animals
Aorta -- cytology -- drug effects -- physiology
Biological Transport -- drug effects
Calcium -- metabolism
Chromans -- chemistry
Cromakalim -- chemistry -- pharmacology
Dose-Response Relationship, Drug
Insulin -- secretion
Insulin-Secreting Cells -- drug effects -- secretion
Ion Channel Gating -- drug effects
Muscle Contraction -- drug effects
Potassium Channels -- metabolism
Potassium Chloride -- pharmacology
Rats
Stereoisomerism
Structure-Activity Relationship
Sulfur Compounds -- chemistry
Note : JOURNAL ARTICLE
SCOPUS: ar.j
Langue :
Identificateurs : urn:issn:0223-5234 
info:doi/10.1016/j.ejmech.2014.04.024
info:pii/S0223-5234(14)00343-2
info:pmid/24763361