Titre :
  • Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: a rationale to combine targeted drugs based on protein expression inhibition profiles.
Auteur : Aftimos, Philippe ; Wiedig, Murielle ; LANGOUO FONTSA, Mireille LFM ; Awada, Ahmad ; Ghanem, Ghanem Elias ; Journé, Fabrice
Informations sur la publication : International journal of oncology, 43, 3, (page 919-926)
Statut de publication : Publié, 2013-09
Sujet CREF : Cancérologie
Médecine pathologie humaine
Sciences bio-médicales et agricoles
Mots-clés MeSH : Cell Line, Tumor
Gene Expression Regulation, Neoplastic -- drug effects
Humans
Janus Kinases -- antagonists & inhibitors
MAP Kinase Kinase Kinases -- antagonists & inhibitors
Melanoma -- drug therapy -- genetics -- pathology
Molecular Targeted Therapy
Phosphatidylinositol 3-Kinases -- antagonists & inhibitors
Protein Kinase Inhibitors -- administration & dosage
Signal Transduction -- drug effects -- genetics
Transcriptome -- drug effects
src-Family Kinases -- antagonists & inhibitors
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:1019-6439 
info:doi/10.3892/ijo.2013.2008
info:pmid/23835698
info:ulb-repo/set/1#14531