Titre:
  • Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: a rationale to combine targeted drugs based on protein expression inhibition profiles.
Auteur:Aftimos, Philippe; Wiedig, Murielle; LANGOUO FONTSA, Mireille LFM; Awada, Ahmad; Ghanem, Ghanem Elias; Journé, Fabrice
Informations sur la publication:International journal of oncology, 43, 3, page (919-926)
Statut de publication:Publié, 2013-09
Sujet CREF:Cancérologie
Médecine pathologie humaine
Sciences bio-médicales et agricoles
MeSH keywords:Cell Line, Tumor
Gene Expression Regulation, Neoplastic -- drug effects
Humans
Janus Kinases -- antagonists & inhibitors
MAP Kinase Kinase Kinases -- antagonists & inhibitors
Melanoma -- drug therapy -- genetics -- pathology
Molecular Targeted Therapy
Phosphatidylinositol 3-Kinases -- antagonists & inhibitors
Protein Kinase Inhibitors -- administration & dosage
Signal Transduction -- drug effects -- genetics
Transcriptome -- drug effects
src-Family Kinases -- antagonists & inhibitors
Note générale:Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:1019-6439
info:doi/10.3892/ijo.2013.2008
info:scp/84880615410
info:pmid/23835698
info:ulb-repo/set/1#14531