Titre:
  • Population pharmacokinetic modeling and optimal sampling strategy for Bayesian estimation of amikacin exposure in critically ill septic patients.
Auteur:Delattre, Isabelle K; Musuamba, Flora T; Nyberg, J.; Taccone, Fabio; Laterre, Pierre-Francois; Verbeeck, Roger K.; Jacobs, Frédérique; Wallemacq, Pierre
Informations sur la publication:Therapeutic drug monitoring, 32, 6, page (749-756)
Statut de publication:Publié, 2010-12
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:amikacin
Bayesian estimation
optimal sampling strategy
population pharmacokinetics
severe sepsis
MeSH keywords:Adult
Aged
Aged, 80 and over
Amikacin -- pharmacokinetics -- therapeutic use
Anti-Bacterial Agents -- pharmacokinetics -- therapeutic use
Bayes Theorem
Creatinine -- blood
Critical Illness
Drug Monitoring -- methods
Female
Humans
Male
Metabolic Clearance Rate
Middle Aged
Models, Biological
Sepsis -- blood -- drug therapy
Tissue Distribution
Note générale:Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0163-4356
info:doi/10.1097/FTD.0b013e3181f675c2
info:scp/78650277930
info:pmid/20962708