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Increased basal and alum-induced interleukin-6 levels in geriatric patients are associated with cardiovascular morbidity.

par Compte, Nathalie ;Zouaoui Boudjeltia, Karim ;Vanhaeverbeek, Michel ;De Breucker, Sandra ;Pepersack, Thierry ;Tassignon, Joël ;Trelcat, Anne;Goriely, Stanislas
Référence PloS one, 8, 11, page (e81911)
Publication Publié, 2013

Article révisé par les pairs

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Résumé :

Low-grade systemic inflammation was suggested to participate to the decline of physiological functions and increased vulnerability encountered in older patients. Geriatric syndromes encompass various features such as functional dependence, polymorbidity, depression and malnutrition. There is a strong prevalence of cardiovascular diseases and related risk factors and chronic cytomegalovirus infections in the geriatric population. As these underlying conditions were proposed to influence the inflammatory state, the aim of this study was to assess their potential contribution to the association of geriatric syndromes with inflammatory parameters.