Article révisé par les pairs
Titre:
  • Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia.
Auteur:Gottesfeld, Joel M; Rusche, James R; Pandolfo, Massimo
Informations sur la publication:Journal of neurochemistry, 126 Suppl 1, page (147-154)
Statut de publication:Publié, 2013-08
Sujet CREF:Neurologie
Mots-clés:Friedreich's ataxia
heterochromatin
histone deacetylase inhibitor
neurodegenerative disorder
MeSH keywords:Animals
Clinical Trials as Topic
Gene Expression -- physiology
Gene Silencing
Heterochromatin -- metabolism
Histone Deacetylase Inhibitors -- chemistry -- therapeutic use
Humans
Iron-Binding Proteins -- biosynthesis -- drug effects -- genetics
Mice
Structure-Activity Relationship
Note générale:Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
FLWIN
SCOPUS: re.j
Langue:Anglais
Identificateurs:urn:issn:0022-3042
info:doi/10.1111/jnc.12302
info:scp/84880354651
info:pmid/23859350