Titre:
  • RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.
Auteur:Cnop, Miriam; Abdulkarim, Baroj; Bottu, Guy; Andrade Da Cunha, Daniel; Igoillo Esteve, Mariana; Masini, Matilde; Turatsinze, Jean Valéry; Griebel, Thasso; Villate, Olatz; Santin Gomez, Izortze; Bugliani, Marco; Ladrière, Laurence; Marselli, Lorella; McCarthy, Mark I; Marchetti, Piero; Sammeth, Michael; Eizirik, Decio L.
Informations sur la publication:Diabetes, 63, page (1978-93)
Statut de publication:Publié, 2014
Sujet CREF:Biologie
Biologie moléculaire
Biologie cellulaire
Biologie générale
Diabétologie
MeSH keywords:Animals
Apoptosis -- drug effects -- genetics
Blotting, Western
Cell Line
Cells, Cultured
Diabetes Mellitus, Type 2 -- genetics -- metabolism
Endoplasmic Reticulum Stress -- drug effects -- genetics
Female
Gene Expression Regulation, Enzymologic
Genetic Predisposition to Disease
Humans
Inflammation -- genetics -- metabolism
Islets of Langerhans -- drug effects -- metabolism
Male
Palmitates -- metabolism
Sequence Analysis, RNA
Signal Transduction
Transcriptome
Note générale:JOURNAL ARTICLE
SCOPUS: ar.j
Langue:Autre
Identificateurs:urn:issn:0012-1797
info:doi/10.2337/db13-1383
info:pii/db13-1383
info:scp/84900334812
info:pmid/24379348