Titre :
  • Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53.
Auteur : Reschner, Anca ; Bontems, S. ; Le Gac, Stéphane ; Lambermont, Javiera ; Marcelis, Lionel ; Defrancq, Eric ; Moucheron, Cécile ; Kirsch-De Mesmaeker, Andrée ; Raes, Martine ; Piette, Jacques ; Delvenne, Philippe O
Informations sur la publication : Gene therapy, 20, 4, (page 435-443)
Statut de publication : Publié, 2013
Sujet CREF : Photochimie
Mots-clés : antisense therapy
carcinoma
oligonucleotides
photoreactive complex
phototherapy
ruthenium
Mots-clés MeSH : Cell Line, Tumor
Cell Proliferation -- drug effects
Cross-Linking Reagents -- chemistry
Female
Gene Silencing
Genes, p53
Genetic Therapy
Humans
Light
Oligonucleotides -- chemistry -- genetics
Oncogene Proteins, Viral -- genetics -- metabolism
Repressor Proteins -- genetics -- metabolism
Ruthenium Compounds -- chemistry -- radiation effects
Tumor Suppressor Protein p53 -- metabolism
Uterine Cervical Neoplasms -- therapy -- virology
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0969-7128 
info:doi/10.1038/gt.2012.54
info:pii/gt201254
info:pmid/22809997