Titre:
  • CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point.
Auteur:Bisteau, Xavier; Paternot, Sabine; Colleoni, Bianca; Ecker, Karin; Coulonval, Katia; De Groote, Philippe; Declercq, Wim; Hengst, Ludger; Roger, Pierre P.
Informations sur la publication:PLOS genetics, 9, 5, page (e1003546)
Statut de publication:Publié, 2013-05
Sujet CREF:Sciences biomédicales en général
Physiologie de la régulation
Croissance et développement [humain]
Croissance et développement [animal]
Sciences biomédicales
MeSH keywords:Cell Cycle Checkpoints -- genetics
Cyclin-Dependent Kinase 2 -- genetics -- metabolism
Cyclin-Dependent Kinase 4 -- genetics -- metabolism
Cyclin-Dependent Kinases -- genetics -- metabolism
G1 Phase Cell Cycle Checkpoints -- genetics
HCT116 Cells
Humans
Mutation
Phosphorylation
Protein Binding
cdc25 Phosphatases -- metabolism
p21-Activated Kinases -- genetics -- metabolism
Note générale:Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:1553-7390
info:doi/10.1371/journal.pgen.1003546
info:pii/PGENETICS-D-12-02954
info:scp/84878506959
info:pmid/23737759
PMC3667761