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Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials.

par De Laurentiis, Michele;Cancello, Giuseppe;D'Agostino, Diego;Giuliano, Mario;Giordano, Antonio;Montagna, Emilia;Lauria, Rossella;Forestieri, Valeria;Esposito, Angela;Silvestro, Lucrezia;Pennacchio, Roberta;Criscitiello, Carmen ;Montanino, Agnese;Limite, Gennaro;Bianco, Angelo Raffaele;De Placido, Sabino
Référence Journal of clinical oncology, 26, 1, page (44-53)
Publication Publié, 2008-01

Article révisé par les pairs

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Résumé :

We conducted a meta-analysis of randomized trials that evaluated the efficacy of incorporating taxanes into anthracycline-based regimens for early breast cancer (EBC). We aimed to determine whether this approach improves disease-free survival (DFS) and overall survival (OS) and whether benefits are maintained across relevant patient subgroups.