Titre:
  • Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Auteur:Kolstoe, Simon E; Mangione, Palma P; Bellotti, Vittorio; Taylor, Graham W; Tennent, Glenys A; Deroo, Stéphanie; Morrison, Angus J; Cobb, Alexander J A; Coyne, Anthony; McCammon, Margaret G; Warner, Timothy D; Mitchell, Janet; Gill, Raj; Smith, Martin D; Ley, Steven V.; Robinson, Carol V; Wood, Stephen P; Pepys, Mark B
Informations sur la publication:Proceedings of the National Academy of Sciences of the United States of America, 107, 47, page (20483-20488)
Statut de publication:Publié, 2010
Sujet CREF:Sciences bio-médicales et agricoles
Sciences pharmaceutiques
MeSH keywords:Amyloid -- biosynthesis -- metabolism
Amyloidosis -- drug therapy -- metabolism
Animals
Calorimetry, Differential Scanning
Chromatography, Gel
Crystallography, X-Ray
Fenamates -- chemical synthesis -- chemistry -- metabolism -- pharmacokinetics
Fluorometry
Ligands
Mass Spectrometry
Mice
Models, Molecular
Molecular Structure
Prealbumin -- metabolism
Ultracentrifugation
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0027-8424
info:doi/10.1073/pnas.1008255107
info:pii/1008255107
info:pmid/21059958
PMC2996680