Titre :
  • Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis.
Auteur : Allagnat, Florent ; Christulia, Foteini ; Ortis, Fernanda ; Pirot, Pierre ; Lortz, Stephan ; Lenzen, Sigurd ; Eizirik, Decio L. ; Cardozo, Alessandra K
Informations sur la publication : Diabetologia, 53, 6, (page 1120-1130)
Statut de publication : Publié, 2010
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Analysis of Variance
Animals
Apoptosis -- drug effects -- physiology
Blotting, Western
Cell Count
Cell Survival -- drug effects
Cells, Cultured
DNA-Binding Proteins -- genetics -- metabolism
Endoplasmic Reticulum -- drug effects -- genetics -- metabolism
Fluorescent Antibody Technique
Homeodomain Proteins -- genetics -- metabolism
Indoles -- pharmacology
Insulin -- genetics -- metabolism -- secretion
Insulin-Secreting Cells -- cytology -- drug effects -- metabolism
Interferon-gamma -- pharmacology
Interleukin-8 -- pharmacology
Maf Transcription Factors -- genetics -- metabolism
Male
RNA Interference
RNA, Small Interfering
Rats
Rats, Wistar
Reverse Transcriptase Polymerase Chain Reaction
Trans-Activators -- genetics -- metabolism
Transcription Factors -- genetics -- metabolism
Transfection
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0012-186X 
info:doi/10.1007/s00125-010-1699-7
info:pmid/20349222