Titre:
  • Somatic Mutation Profiling and Associations With Prognosis and Trastuzumab Benefit in Early Breast Cancer.
Auteur:Loi, Sherene; Michiels, Stefan; Lambrechts, Diether; Fumagalli, Debora; Claes, Bart; Kellokumpu-Lehtinen, Pirkko-Liisa; Bono, Petri; Kataja, Vesa; Piccart-Gebhart, Martine; Joensuu, Heikki; Sotiriou, Christos
Informations sur la publication:Journal of the National Cancer Institute, 105, 13, page (960-967)
Statut de publication:Publié, 2013-07-03
Sujet CREF:Cancérologie
Sciences biomédicales
MeSH keywords:Adult
Aged
Antibodies, Monoclonal, Humanized -- therapeutic use
Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
Base Sequence
Breast Neoplasms -- drug therapy -- genetics -- mortality -- pathology
Cyclophosphamide -- administration & dosage
Disease-Free Survival
Drug Administration Schedule
Early Detection of Cancer
Epirubicin -- administration & dosage
Female
Finland -- epidemiology
Fluorouracil -- administration & dosage
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Humans
Kaplan-Meier Estimate
Lymphatic Metastasis
Middle Aged
Molecular Sequence Data
Mutation
Neoplasm Staging
Phosphatidylinositol 3-Kinases -- genetics
Predictive Value of Tests
Prognosis
Proportional Hazards Models
Receptor, ErbB-2 -- genetics
Taxoids -- administration & dosage
Treatment Outcome
Tumor Markers, Biological -- genetics
Vinblastine -- administration & dosage -- analogs & derivatives
Note générale:JOURNAL ARTICLE
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0027-8874
info:doi/10.1093/jnci/djt121
info:pii/djt121
info:scp/84880230412
info:pmid/23739063