Titre:
  • Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR.
Auteur:Ersoy, Baran A; Pardo, Leonardo; Zhang, Sumei; Thompson, Darren A; Millhauser, Glenn; Govaerts, Cédric; Vaisse, Christian
Informations sur la publication:Nature Chemical Biology, 8, 8, page (725-730)
Statut de publication:Publié, 2012-08
Sujet CREF:Sciences biomédicales
Médecine pathologie humaine
Ingénierie biomédicale
Sciences bio-médicales et agricoles
MeSH keywords:Agouti-Related Protein -- metabolism
Cell Membrane
Gene Expression Regulation -- physiology
HEK293 Cells
Humans
Models, Molecular
Plasmids
Protein Conformation
Protein Structure, Tertiary
Receptor, Melanocortin, Type 4 -- agonists -- genetics -- metabolism
alpha-MSH -- genetics -- metabolism
Note générale:Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:1552-4450
info:doi/10.1038/nchembio.1008
info:pii/nchembio.1008
info:scp/84864290272
info:pmid/22729149
PMC3657613