par Eizirik, Decio L. ;Cnop, Miriam
Référence Cell Metabolism, 16, 5, page (555-557)
Publication Publié, 2012
Article révisé par les pairs
Résumé : Pancreatic β cell failure is central in the pathogenesis of type 2 diabetes (T2D), but the mechanisms involved remain unclear. Mahdi and colleagues (2012) couple global evaluation of gene expression with coexpression network analysis of human islets from T2D patients to identify SFRP4 as an early mediator of β cell dysfunction in T2D.