Titre:
  • Mild endoplasmic reticulum stress augments the proinflammatory effect of IL-1beta in pancreatic rat beta-cells via the IRE1alpha/XBP1s pathway.
Auteur:Miani, MICHELA; Colli, Maikel L; Ladrière, Laurence; Cnop, Miriam; Eizirik, Decio L.
Informations sur la publication:Endocrinology, 153, 7, page (3017-3028)
Statut de publication:Publié, 2012
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Apoptosis
DNA-Binding Proteins -- metabolism
Endoplasmic Reticulum -- metabolism
Endoribonucleases -- metabolism
Genes, Reporter
Inflammation
Insulin-Secreting Cells -- cytology
Insulinoma -- metabolism
Interleukin-1beta -- metabolism
Male
Microscopy, Fluorescence -- methods
Models, Biological
Multienzyme Complexes -- metabolism
NF-kappa B -- metabolism
Protein-Serine-Threonine Kinases -- metabolism
RNA Interference
Rats
Rats, Wistar
Transcription Factors -- metabolism
Note générale:Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0013-7227
info:doi/10.1210/en.2011-2090
info:pii/en.2011-2090
info:scp/84862742723
info:pmid/22529213