Titre :
  • C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in beta-cells.
Auteur : Allagnat, Florent ; Fukaya, Makiko ; Nogueira, Tatiane C ; Delaroche, Diane ; Welsh, N ; Marselli, L ; Marchetti, Piero ; Haefliger, J A ; Eizirik, Decio L. ; Cardozo, Alessandra K
Informations sur la publication : Cell death and differentiation, 19, 11, (page 1836-1846)
Statut de publication : Publié, 2012
Sujet CREF : Sciences biomédicales
Sciences bio-médicales et agricoles
Mots-clés : apoptosis
Bcl-2 proteins
CHOP
ER stress
inflammation
pancreatic b-cell
Mots-clés MeSH : Animals
Apoptosis -- drug effects
Caspase 3 -- metabolism
Caspase 9 -- metabolism
Cell Line
Cell Nucleus -- metabolism
Cytokines -- pharmacology
Diabetes Mellitus, Type 1 -- metabolism -- pathology
Endoplasmic Reticulum Stress
I-kappa B Kinase -- metabolism
Insulin-Secreting Cells -- cytology -- metabolism
Interferon-gamma -- pharmacology
Interleukin-1beta -- pharmacology
Mitochondria -- metabolism
NF-kappa B -- metabolism
Proto-Oncogene Proteins c-bcl-2 -- metabolism
Rats
Transcription Factor CHOP -- antagonists & inhibitors -- genetics -- metabolism
Transcription Factor RelA -- metabolism
Tumor Necrosis Factor-alpha -- pharmacology
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:1350-9047 
info:doi/10.1038/cdd.2012.67
info:pii/cdd201267
info:pmid/22653339