Titre :
  • Differential usage of NF-kappaB activating signals by IL-1beta and TNF-alpha in pancreatic beta cells.
Auteur : Ortis, Fernanda ; Miani, MICHELA ; Colli, M L ; Andrade Da Cunha, Daniel ; Gurzov, E N ; Allagnat, Florent ; Chariot, Alain ; Eizirik, Decio L.
Informations sur la publication : FEBS letters, 586, 7, (page 984-989)
Statut de publication : Publié, 2012
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Cytokine
IKK complex
Interleukin-1β
NF-κB
Pancreatic β-cell
Mots-clés MeSH : Animals
Cell Line
Cells, Cultured
Diabetes Mellitus, Type 1 -- drug therapy
Gene Silencing
Humans
I-kappa B Kinase -- antagonists & inhibitors -- genetics -- metabolism
Insulin-Secreting Cells -- cytology -- drug effects -- metabolism
Interleukin-1beta -- metabolism
Mice
Molecular Targeted Therapy
NF-kappa B -- metabolism
Protease Inhibitors -- pharmacology
Proteasome Endopeptidase Complex -- metabolism
Proteasome Inhibitors
Protein Kinase Inhibitors -- pharmacology
Protein Subunits -- antagonists & inhibitors -- genetics -- metabolism
Proteolysis -- drug effects
Rats
Rats, Wistar
Recombinant Proteins -- metabolism
Signal Transduction -- drug effects
Tumor Necrosis Factor-alpha -- genetics -- metabolism
Note : Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0014-5793 
info:doi/10.1016/j.febslet.2012.02.021
info:pii/S0014-5793(12)00130-5
info:pmid/22569251