Titre:
  • Differential usage of NF-kappaB activating signals by IL-1beta and TNF-alpha in pancreatic beta cells.
Auteur:Ortis, Fernanda; Miani, MICHELA; Colli, M L; Andrade Da Cunha, Daniel; Gurzov, E N; Allagnat, Florent; Chariot, Alain; Eizirik, Decio L.
Informations sur la publication:FEBS letters, 586, 7, page (984-989)
Statut de publication:Publié, 2012
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Cytokine
IKK complex
Interleukin-1β
NF-κB
Pancreatic β-cell
MeSH keywords:Animals
Cell Line
Cells, Cultured
Diabetes Mellitus, Type 1 -- drug therapy
Gene Silencing
Humans
I-kappa B Kinase -- antagonists & inhibitors -- genetics -- metabolism
Insulin-Secreting Cells -- cytology -- drug effects -- metabolism
Interleukin-1beta -- metabolism
Mice
Molecular Targeted Therapy
NF-kappa B -- metabolism
Protease Inhibitors -- pharmacology
Proteasome Endopeptidase Complex -- metabolism
Proteasome Inhibitors
Protein Kinase Inhibitors -- pharmacology
Protein Subunits -- antagonists & inhibitors -- genetics -- metabolism
Proteolysis -- drug effects
Rats
Rats, Wistar
Recombinant Proteins -- metabolism
Signal Transduction -- drug effects
Tumor Necrosis Factor-alpha -- genetics -- metabolism
Note générale:Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0014-5793
info:doi/10.1016/j.febslet.2012.02.021
info:pii/S0014-5793(12)00130-5
info:scp/84859269961
info:pmid/22569251