Titre :
  • AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity.
Auteur : Didierlaurent, Arnaud M ; Morel, Sandra ; Lockman, Laurence ; Giannini, Sandra L ; Bisteau, Michel ; Carlsen, Harald ; Kielland, Anders ; Vosters, Olivier ; Vanderheyde, Nathalie ; Schiavetti, Francesca ; Larocque, Daniel ; Van Mechelen, Marcelle ; Garçon, Nathalie
Informations sur la publication : The Journal of immunology, 183, 10, (page 6186-6197)
Statut de publication : Publié, 2009-11
Sujet CREF : Immunologie
Allergie et immunopathologie
Mots-clés MeSH : Adjuvants, Immunologic -- pharmacology
Aluminum Hydroxide -- pharmacology
Animals
Antigens, CD40 -- immunology -- metabolism
Antigens, CD86 -- immunology -- metabolism
CD4-Positive T-Lymphocytes -- drug effects -- immunology -- metabolism
Cell Line
Cytokines -- drug effects -- immunology -- metabolism
Dendritic Cells -- drug effects -- immunology -- metabolism
Female
Human papillomavirus 16 -- immunology
Human papillomavirus 18 -- immunology
Humans
Immunity, Innate -- drug effects
Lipid A -- analogs & derivatives -- pharmacology
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
NF-kappa B -- agonists -- immunology -- metabolism
Ovalbumin -- immunology
Papillomavirus Infections -- immunology -- virology
Papillomavirus Vaccines -- immunology
Toll-Like Receptor 4 -- agonists -- immunology
Transfection
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0022-1767 
info:doi/10.4049/jimmunol.0901474
info:pii/jimmunol.0901474
info:pmid/19864596