Titre:
  • Bulbispermine: a crinine-type Amaryllidaceae alkaloid exhibiting cytostatic activity toward apoptosis-resistant glioma cells.
Auteur:Luchetti, Giovanni; Johnston, Robert; Mathieu, Véronique; Lefranc, Florence; Hayden, Kathryn; Andolfi, Anna; Lamoral-Theys, Delphine; Reisenauer, Mary R; Champion, Cody; Pelly, Stephen C; van Otterlo, Willem A L; Magedov, Igor V; Kiss, Robert; Evidente, Antonio; Rogelj, Snezna; Kornienko, Alexander
Informations sur la publication:ChemMedChem, 7, 5, page (815-822)
Statut de publication:Publié, 2012-05
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Actin cytoskeletons
Alkaloids
Apoptosis
Bulbispermines
Cancer
Glioblastomas
MeSH keywords:Amaryllidaceae Alkaloids -- chemistry -- pharmacology
Antineoplastic Agents, Phytogenic -- chemistry -- pharmacology
Computer Simulation
Drug Resistance, Neoplasm
Drug Screening Assays, Antitumor
Humans
Inhibitory Concentration 50
Molecular Structure
Plant Roots -- chemistry
Note générale:Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
FLWNA
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:1860-7179
info:doi/10.1002/cmdc.201100608
info:scp/84860253031
info:pmid/22389235