Titre :
  • Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
Auteur : McCormack, Mark ; Urban, Thomas J ; Shianna, Kevin V ; Walley, Nicole ; Pandolfo, Massimo ; Depondt, Chantal ; Chaila, Elijah ; O'Conner, Gerard D ; Kasperavičiūtė, Dalia ; Radtke, Rodney A ; Heinzen, Erin ; Sisodiya, Sanjay M ; Delanty, Norman ; Cavalleri, Gianpiero L
Informations sur la publication : Pharmacogenomics, 13, 4, (page 399-405)
Statut de publication : Publié, 2012-03
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : epilepsy
GWAS
HLA-A 3101
hypersensitivity
lamotrigine
phenytoin
Mots-clés MeSH : Biomarkers, Pharmacological
Carbamazepine -- adverse effects -- therapeutic use
Drug Hypersensitivity -- genetics
Genome-Wide Association Study
HLA-A Antigens -- genetics
Humans
Phenytoin -- adverse effects -- therapeutic use
Polymorphism, Single Nucleotide
Triazines -- adverse effects -- therapeutic use
Note : Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:1462-2416 
info:doi/10.2217/pgs.11.165
info:pmid/22379998