Titre :
  • A phase 1 study of BMS-275183, a novel oral analogue of paclitaxel given on a daily schedule to patients with advanced malignancies.
Auteur : Heath, Elisabeth I ; Lorusso, Patricia ; Ramalingam, Suresh S ; Awada, Ahmad ; Egorin, Merrill J ; Besse-Hammer, Tatiana ; Cardoso, Fatima ; Valdivieso, Manuel ; Has, Teresa ; Alland, Leila ; Zhou, Xiaofei ; Belani, Chandra P
Informations sur la publication : Investigational new drugs, 29, 6, (page 1426-1431)
Statut de publication : Publié, 2011-12
Sujet CREF : Cancérologie
Mots-clés : Oral
Paclitaxel
Phase I
Mots-clés MeSH : Administration, Oral
Aged
Antineoplastic Agents -- administration & dosage -- adverse effects -- pharmacokinetics
Bridged Compounds -- administration & dosage -- adverse effects -- pharmacokinetics
Dose-Response Relationship, Drug
Drug Administration Schedule
Female
Humans
Male
Middle Aged
Neoplasms -- drug therapy -- pathology
Neutropenia -- chemically induced
Sepsis -- chemically induced
Treatment Outcome
Note : Clinical Trial, Phase I
Journal Article
Multicenter Study
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0167-6997 
info:doi/10.1007/s10637-010-9498-z
info:pmid/20680660