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Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials.

par Early Breast Cancer Trialists' Collaborative Group (EBCTCG), S;Darby, P;McGale, C;Correa, C;Taylor, R.;Arriagada, M.J.;Clarke, D;Cutter, C;Davies, M;Ewertz, J;Godwin, Richard;Gray, Kimberly;Pierce, Timothy J;Whelan, Yiwei;Wang, R ;Peto,
Référence Lancet, 378, 9804, page (1707-1716)
Publication Publié, 2011-11

Article révisé par les pairs

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Résumé :

After breast-conserving surgery, radiotherapy reduces recurrence and breast cancer death, but it may do so more for some groups of women than for others. We describe the absolute magnitude of these reductions according to various prognostic and other patient characteristics, and relate the absolute reduction in 15-year risk of breast cancer death to the absolute reduction in 10-year recurrence risk.