Titre :
  • Safety and pharmacokinetics of sorafenib combined with capecitabine in patients with advanced solid tumors: results of a phase 1 trial.
Auteur : Awada, Ahmad ; Gil, Thierry ; Whenham, Nicolas ; Van Hamme, Julie ; Besse-Hammer, Tatiana ; Brendel, Erich ; Delesen, Heinz ; Joosten, Miranda C ; Lathia, Chetan ; Loembé, Bienvenu A ; Piccart-Gebhart, Martine ; Hendlisz, Alain
Informations sur la publication : Journal of clinical pharmacology, 51, 12, (page 1674-1684)
Statut de publication : Publié, 2011-12
Sujet CREF : Cancérologie
Mots-clés MeSH : Adult
Aged
Antineoplastic Agents -- administration & dosage
Antineoplastic Combined Chemotherapy Protocols -- adverse effects -- blood -- pharmacokinetics
Area Under Curve
Benzenesulfonates -- administration & dosage
Colonic Neoplasms -- drug therapy -- metabolism
Deoxycytidine -- administration & dosage -- analogs & derivatives
Diarrhea -- chemically induced
Fatigue -- chemically induced
Female
Fluorouracil -- administration & dosage -- analogs & derivatives
Hand-Foot Syndrome -- etiology
Humans
Male
Middle Aged
Neoplasms -- drug therapy -- metabolism
Protein Kinase Inhibitors -- administration & dosage
Pyridines -- administration & dosage
Note : Clinical Trial, Phase I
Journal Article
Research Support, Non-U.S. Gov't
FLWIN
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0091-2700 
info:doi/10.1177/0091270010386226
info:pii/0091270010386226
info:pmid/21209247