Article révisé par les pairs
Titre :
  • Inactivation of adenosine A2A receptor attenuates basal and angiotensin II-induced ROS production by Nox2 in endothelial cells.
Auteur : Thakur, Sapna ; Du, J. ; Hourani, Susanna ; Ledent, Catherine ; Li, Jian-Mei
Informations sur la publication : The Journal of biological chemistry, 285, 51, (page 40104-40113)
Statut de publication : Publié, 2010-12
Sujet CREF : Sciences biomédicales
Mots-clés MeSH : Adenosine A2 Receptor Antagonists -- pharmacology
Angiotensin II -- metabolism -- pharmacology
Animals
Cells, Cultured
Endothelial Cells -- metabolism
Enzyme Activation -- drug effects -- genetics
Gene Expression Regulation, Enzymologic -- drug effects -- genetics
Membrane Glycoproteins -- genetics -- metabolism
Mice
Mice, Knockout
Mitogen-Activated Protein Kinase 3 -- genetics -- metabolism
NADPH Oxidase -- biosynthesis -- genetics -- metabolism
Phosphorylation -- drug effects -- genetics
Proto-Oncogene Proteins c-akt -- genetics -- metabolism
Pyrimidines -- pharmacology
Reactive Oxygen Species -- metabolism
Receptor, Adenosine A2A -- genetics -- metabolism
Signal Transduction -- drug effects -- physiology
Triazoles -- pharmacology
p38 Mitogen-Activated Protein Kinases -- genetics -- metabolism
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0021-9258 
info:doi/10.1074/jbc.M110.184606
info:pii/M110.184606
info:pmid/20940302
info:pmcid/PMC3000993