Titre :
  • A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases.
Auteur : Body, Jean-Jacques ; Greipp, Philip ; Coleman, Robert ; Facon, Thierry ; Geurs, Filip ; Fermand, Jean-Paul ; Harousseau, Jean-Luc ; Lipton, Allan ; Mariette, Xavier ; Williams, Catherine ; Nakanishi, Arline ; Holloway, Donna ; Martin, Steven ; Dunstan, Colin ; Bekker, Pirow
Informations sur la publication : Cancer, 97, 3 Suppl, (page 887-892)
Statut de publication : Publié, 2003-02
Sujet CREF : Cancérologie
Mots-clés MeSH : Antineoplastic Agents -- administration & dosage -- pharmacokinetics -- therapeutic use
Bone Neoplasms -- drug therapy -- secondary
Bone Resorption -- drug therapy -- metabolism
Breast Neoplasms -- pathology
Diphosphonates -- administration & dosage -- pharmacokinetics -- therapeutic use
Dose-Response Relationship, Drug
Double-Blind Method
Female
Glycoproteins -- administration & dosage -- pharmacokinetics -- therapeutic use
Humans
Male
Middle Aged
Multiple Myeloma -- drug therapy
Osteoprotegerin
Receptors, Cytoplasmic and Nuclear -- administration & dosage -- therapeutic use
Receptors, Tumor Necrosis Factor
Treatment Outcome
Note : Clinical Trial
Clinical Trial, Phase I
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
FLWIN
Langue :
  • Anglais
Identificateurs : urn:issn:0008-543X 
info:doi/10.1002/cncr.11138
info:pmid/12548591