Titre:
  • A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases.
Auteur:Body, Jean-Jacques; Greipp, Philip; Coleman, Robert; Facon, Thierry; Geurs, Filip; Fermand, Jean-Paul; Harousseau, Jean-Luc; Lipton, Allan; Mariette, Xavier; Williams, Catherine; Nakanishi, Arline; Holloway, Donna; Martin, Steven; Dunstan, Colin; Bekker, Pirow
Informations sur la publication:Cancer, 97, 3 Suppl, page (887-892)
Statut de publication:Publié, 2003-02
Sujet CREF:Cancérologie
MeSH keywords:Antineoplastic Agents -- administration & dosage -- pharmacokinetics -- therapeutic use
Bone Neoplasms -- drug therapy -- secondary
Bone Resorption -- drug therapy -- metabolism
Breast Neoplasms -- pathology
Diphosphonates -- administration & dosage -- pharmacokinetics -- therapeutic use
Dose-Response Relationship, Drug
Double-Blind Method
Female
Glycoproteins -- administration & dosage -- pharmacokinetics -- therapeutic use
Humans
Male
Middle Aged
Multiple Myeloma -- drug therapy
Osteoprotegerin
Receptors, Cytoplasmic and Nuclear -- administration & dosage -- therapeutic use
Receptors, Tumor Necrosis Factor
Treatment Outcome
Note générale:Clinical Trial
Clinical Trial, Phase I
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
FLWIN
Langue:Anglais
Identificateurs:urn:issn:0008-543X
info:doi/10.1002/cncr.11138
info:pmid/12548591