Article révisé par les pairs
Titre:
  • Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases.
Auteur:Lipton, Allan; Steger, Guenther; Figueroa, Jazmin; Alvarado, Cristina; Solal-Celigny, Philippe; Body, Jean-Jacques; De Boer, Richard; Berardi, Rossana; Gascon, Pere; Tonkin, Katia; Coleman, Robert; Paterson, Alexander H. G.; Peterson, Mark C.; Fan, Michelle; Kinsey, Amy C.; Jun, Susie
Informations sur la publication:Journal of clinical oncology, 25, 28, page (4431-4437)
Statut de publication:Publié, 2007-10
Sujet CREF:Cancérologie
MeSH keywords:Adult
Aged
Aged, 80 and over
Antibodies, Monoclonal -- administration & dosage -- adverse effects -- therapeutic use
Biological Markers -- metabolism
Bone Density Conservation Agents -- administration & dosage -- adverse effects -- therapeutic use
Bone Neoplasms -- drug therapy -- secondary
Bone Resorption -- prevention & control
Breast Neoplasms -- pathology
Collagen Type I -- drug effects -- metabolism
Computer Simulation
Double-Blind Method
Drug Administration Schedule
Drug Toxicity
Female
Humans
Infusions, Intravenous
Injections, Subcutaneous
Kaplan-Meier Estimate
Middle Aged
Peptides -- drug effects -- metabolism
RANK Ligand
Note générale:Clinical Trial, Phase II
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0732-183X
info:doi/10.1200/JCO.2007.11.8604
info:pii/JCO.2007.11.8604
info:pmid/17785705

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