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Concomitant chemo-radiotherapy as standard therapy in limited-stage small-cell oesophageal cancer: a summary of 3 clinical cases and review of the literature.

par Vos, Bertrand ;Gallez, Julien;Debroux, Sébastien;Roland, Sandrine;Verhest, Alain ;Van Houtte, Paul ;Awada, Ahmad ;Hendlisz, Alain
Référence Acta gastro-enterologica Belgica (Ed. multilingue), 71, 3, page (325-329)
Publication Publié, 2008

Article révisé par les pairs

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Résumé :

Small-cell carcinoma of the oesophagus (SCCO) is a rare and aggressive malignant tumour associated with a poor prognosis. Between 1994 and 2002, three patients with SCCO were treated in our institution, representing 1.96% (3 out of 153) of all oesophageal malignancies seen during this period. All of these patients had limited-stage SCCO at initial diagnosis and were treated by chemotherapy (cisplatin and etoposide) with concomitant radiotherapy. An initial complete response of the primary lesion was observed in all cases and a persistent complete remission in two of the cases. Chemo-radiotherapy should be considered as a valuable treatment alternative to surgery for limited-stage small-cell carcinoma of the oesophagus.