par Eskinazi, Rally ;Grégoire, Anne ;Svoboda, Michal ;Peny, Marie-Odile ;Adler, Michael ;Robberecht, Patrick ;Van Laethem, Jean-Luc
Référence Gastroenterology, 114, 6, page (1211-1220)
Publication Publié, 1998-06
Référence Gastroenterology, 114, 6, page (1211-1220)
Publication Publié, 1998-06
Article révisé par les pairs
Résumé : | An absence or a presence of mutated transforming growth factor (TGF)-beta receptors is a possible hypothesis explaining the resistance of cancer cells to the growth-inhibitory effect of TGF-beta. Mutations involving microsatellite-like regions of the type II TGF-beta receptor have been described in subgroups of colorectal cancers. The aim of this study was to investigate the expression and distribution of TGF-beta receptors in sporadic colorectal cancers and normal tissues. |