Titre :
  • KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab.
Auteur : De Roock, Wendy ; Piessevaux, Hubert ; De Schutter, Jef ; Janssens, Muriel ; De Hertogh, Gert ; Personeni, Nicola ; Biesmans, Bart ; Van Laethem, Jean-Luc ; Peeters, Michel ; Humblet, Yves ; van Cutsem, Eric ; Tejpar, Sabine
Informations sur la publication : Annals of oncology, 19, 3, (page 508-515)
Statut de publication : Publié, 2008-03
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Cetuximab
Colorectal cancer
EGFR
KRAS
Survival
Mots-clés MeSH : Antibodies, Monoclonal -- therapeutic use
Antineoplastic Agents -- therapeutic use
Antineoplastic Combined Chemotherapy Protocols
Camptothecin -- administration & dosage -- analogs & derivatives
Colorectal Neoplasms -- drug therapy -- genetics -- mortality -- radiography
Disease-Free Survival
Female
Humans
Logistic Models
Male
Middle Aged
Mutation
Proportional Hazards Models
Proto-Oncogene Proteins -- analysis
Retrospective Studies
Sensitivity and Specificity
Survival Rate
Tomography, X-Ray Computed
ras Proteins -- analysis
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0923-7534 
info:doi/10.1093/annonc/mdm496
info:pii/mdm496
info:pmid/17998284