Titre :
  • Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis.
Auteur : Mathys, Vanessa ; Wintjens, René ; Lefèvre, Philippe ; Bertout, Julie ; Singhal, Amit ; Kiass, Mehdi ; Kurepina, Natalia ; Wang, Xiao-Jing ; Mathema, Barun ; Baulard, Alain ; Kreiswirth, Barry N ; Bifani, Juan Pablo
Informations sur la publication : Antimicrobial agents and chemotherapy, 53, 5, (page 2100-2109)
Statut de publication : Publié, 2009-05
Sujet CREF : Biologie
Mots-clés : Biologie structurale
Mots-clés MeSH : Aminosalicylic Acid -- pharmacology
Antitubercular Agents -- pharmacology
Bacterial Proteins -- genetics
Drug Resistance, Bacterial -- genetics
Folic Acid -- biosynthesis
Humans
Microbial Sensitivity Tests
Mutation
Mycobacterium tuberculosis -- drug effects -- enzymology -- genetics
Structure-Activity Relationship
Thymidylate Synthase -- genetics
Thymine -- biosynthesis
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0066-4804 
info:doi/10.1128/AAC.01197-08
info:pii/AAC.01197-08
info:pmid/19237648
info:pmcid/PMC2681553